Roy Golsteyn: search on Z-Library

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1

ChemInform Abstract: A Three-Step Synthesis from Rebeccamycin of an Efficient Checkpoint Kinase 1 Inhibitor.

Fabrice Anizon, Roy M. Golsteyn, Stephane Leonce, Bruno Pfeiffer, Michelle Prudhomme

Journal:

Year:

2009

File:

PDF, 24 KB

2009

2

Synthesis and biological evaluation of new dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones, substituted with various saturated and unsaturated side chains via palladium catalyzed cross-coupling reactions

Hélène Hénon, Fabrice Anizon, Roy M. Golsteyn, Stéphane Léonce, Robert Hofmann, Bruno Pfeiffer, Michelle Prudhomme

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 188 KB

english, 2006

3

Synthesis and biological activities of isogranulatimide analogues

Bernadette Hugon, Fabrice Anizon, Christian Bailly, Roy M. Golsteyn, Alain Pierré, Stéphane Léonce, John Hickman, Bruno Pfeiffer, Michelle Prudhomme

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 457 KB

english, 2007

4

Synthesis and biological activities of 7-aza rebeccamycin analogues bearing the sugar moiety on the nitrogen of the pyridine ring

Samir Messaoudi, Fabrice Anizon, Paul Peixoto, Marie-Hélène David-Cordonnier, Roy M. Golsteyn, Stéphane Léonce, Bruno Pfeiffer, Michelle Prudhomme

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 385 KB

english, 2006

5

Synthesis, checkpoint kinase 1 inhibitory properties and in vitro antiproliferative activities of new pyrrolocarbazoles

Elisabeth Conchon, Fabrice Anizon, Bettina Aboab, Roy M. Golsteyn, Stéphane Léonce, Bruno Pfeiffer, Michelle Prudhomme

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 1.05 MB

english, 2008

6

Novel 5-azaindolocarbazoles as cytotoxic agents and Chk1 inhibitors

Myriam Lefoix, Gérard Coudert, Sylvain Routier, Bruno Pfeiffer, Daniel-Henri Caignard, John Hickman, Alain Pierré, Roy M. Golsteyn, Stéphane Léonce, Céline Bossard, Jean-Yves Mérour

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 349 KB

english, 2008

7

Synthesis and CHK1 inhibitory potency of Hymenialdisine analogues

Jean-Gilles Parmentier, Bernard Portevin, Roy M. Golsteyn, Alain Pierré, John Hickman, Philippe Gloanec, Guillaume De Nanteuil

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 155 KB

english, 2009

8

Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of indolylpyrazolones and indolylpyridazinedione

Elisabeth Conchon, Bettina Aboab, Roy M. Golsteyn, Francisco Cruzalegui, Thomas Edmonds, Stéphane Léonce, Bruno Pfeiffer, Michelle Prudhomme

Journal:

European Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 449 KB

english, 2006

9

Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of pyrrolo[3,4-a]carbazole-1,3-diones, pyrrolo[3,4-c]carbazole-1,3-diones, and 2-aminopyridazino[3,4-a]pyrrolo[3,4-c]carbazole-1,3,4,7-tetraone

Elisabeth Conchon, Fabrice Anizon, Bettina Aboab, Roy M. Golsteyn, Stéphane Léonce, Bruno Pfeiffer, Michelle Prudhomme

Journal:

European Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 552 KB

english, 2008

10

Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of dipyrrolo[3,4-a:3,4-c]carbazole-triones

Elisabeth Conchon, Fabrice Anizon, Roy M. Golsteyn, Stéphane Léonce, Bruno Pfeiffer, Michelle Prudhomme

Journal:

Year:

2006

Language:

english

File:

PDF, 366 KB

english, 2006

11

An expeditious multigram preparation of the marine protein kinase inhibitor debromohymenialdisine

Bernard Portevin, Roy M. Golsteyn, Alain Pierré, Guillaume De Nanteuil

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 124 KB

english, 2003

12

Synthesis of a staurosporine analogue possessing a 7-azaindole unit instead of an indole moiety

Samir Messaoudi, Fabrice Anizon, Bruno Pfeiffer, Roy Golsteyn, Michelle Prudhomme

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 294 KB

english, 2004

13

Evaluation of permethrin for the protection of cattle against mosquitoes (diptera: Culicidae), applied as electrostatic and low pressure sprays

Joseph A. Shemanchuk, Roy W. Spooner, Lorraine R. Golsteyn

Journal:

Pest Management Science

Year:

1991

Language:

english

File:

PDF, 311 KB

english, 1991

14

A three-step synthesis from rebeccamycin of an efficient checkpoint kinase 1 inhibitor

Fabrice Anizon, Roy M. Golsteyn, Stéphane Léonce, Bruno Pfeiffer, Michelle Prudhomme

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 235 KB

english, 2009

15

10.1038/35087009

Fradelizi, Julie, Noireaux, Vincent, Plastino, Julie, Menichi, Bernadette, Louvard, Daniel, Sykes, Cécile, Golsteyn, Roy M., Friederich, Evelyne

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 1.03 MB

english, 2001

16

The dynamics of actin-based motility depend on surface parameters

Bernheim-Groswasser, Anne, Wiesner, Sebastian, Golsteyn, Roy M., Carlier, Marie-France, Sykes, Cécile

Journal:

Year:

2002

Language:

english

File:

PDF, 222 KB

english, 2002

17

Bis-imide granulatimide analogues as potent Checkpoint 1 kinase inhibitors

Hélène Hénon, Samir Messaoudi, Fabrice Anizon, Bettina Aboab, Nathalie Kucharczyk, Stéphane Léonce, Roy M. Golsteyn, Bruno Pfeiffer, Michelle Prudhomme

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 452 KB

english, 2007

18

Following comets

Roy M. Golsteyn

Journal:

Current Biology

Year:

1998

Language:

english

File:

PDF, 105 KB

english, 1998

19

Mining the genome for SPECs of enlightenment

Journal:

Trends in Cell Biology

Year:

2000

Language:

english

File:

PDF, 37 KB

english, 2000

20

Placing Ena/VASP proteins onto the circle of actin dynamics

Journal:

Trends in Cell Biology

Year:

2000

Language:

english

File:

PDF, 94 KB

english, 2000

21

When being right is not enough

Journal:

Trends in Cell Biology

Year:

2001

Language:

english

File:

PDF, 15 KB

english, 2001

22

French cell biologist receives government award

Journal:

Trends in Cell Biology

Year:

2001

Language:

english

File:

PDF, 15 KB

english, 2001

23

The position of Chk1 in cancer research

Roy M. Golsteyn

Journal:

Trends in Cell Biology

Year:

2001

Language:

english

File:

PDF, 16 KB

english, 2001

24

Rushing to fill scientific positions in Canada

Journal:

Trends in Cell Biology

Year:

2001

Language:

english

File:

PDF, 23 KB

english, 2001

25

All scientists, great and small: Great Feuds in Science, by Hal Hellman

Roy M. Golsteyn

Journal:

Trends in Cell Biology

Year:

1999

Language:

english

File:

PDF, 58 KB

english, 1999

26

Biology

Burkhard Haefner, Roy M Golsteyn, Michael R Seringhaus, Rob Hooft van Huijsduijnen, Olfa Hooft van Huijsduijnen, Leodevico L Ilag, Alex Gaither, Victoria Heath, Dipak K Sarker

Journal:

Drug Discovery Today

Year:

2004

Language:

english

File:

PDF, 69 KB

english, 2004

27

The story of gefitinib, an EGFR kinase that works in lung cancer

Roy M. Golsteyn

Journal:

Drug Discovery Today

Year:

2004

Language:

english

File:

PDF, 193 KB

english, 2004

28

Gefitinib does not increase survival in lung cancer patients

Roy M. Golsteyn

Journal:

Drug Discovery Today

Year:

2005

Language:

english

File:

PDF, 79 KB

english, 2005

29

Characterization of Polo-like Kinase 1 during Meiotic Maturation of the Mouse Oocyte

Golbahar Pahlavan, Zbigniew Polanski, Petr Kalab, Roy Golsteyn, Erich A. Nigg, Bernard Maro

Journal:

Developmental Biology

Year:

2000

Language:

english

File:

PDF, 405 KB

english, 2000

30

Protein kinase C and meiotic maturation of surf clam oocytes

François Dubé, Roy Golsteyn, Louise Dufresne

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 326 KB

english, 1987

31

Cdk1 and Cdk2 complexes (cyclin dependent kinases) in apoptosis: a role beyond the cell cycle

Roy M. Golsteyn

Journal:

Year:

2005

Language:

english

File:

PDF, 172 KB

english, 2005

32

An unusual DNA binding compound, S23906, induces mitotic catastrophe in cultured human cells

Nathalie Cahuzac, Aurélie Studény, Kris Marshall, Isabella Versteege, Kate Wetenhall, Bruno Pfeiffer, Stéphane Léonce, John A. Hickman, Alain Pierré, Roy M. Golsteyn

Journal:

Year:

2010

Language:

english

File:

PDF, 890 KB

english, 2010

33

Duration of pregnancy and risk of breast cancer

Hèléne Lapillonne, Roy M Golsteyn, Alexandre Lapillonne

Journal:

Year:

1999

Language:

english

File:

PDF, 60 KB

english, 1999

34

Phosphorylation of CDC25C at S263 controls its intracellular localisation

Charlotte Esmenjaud-Mailhat, Valérie Lobjois, Carine Froment, Roy M. Golsteyn, Bernard Monsarrat, Bernard Ducommun

Journal:

Year:

2007

Language:

english

File:

PDF, 708 KB

english, 2007

35

A western blot assay to measure cyclin dependent kinase activity in cells or in vitro without the use of radioisotopes

Lewis, Cody W., Taylor, Ryan G., Kubara, Philip M., Marshall, Kris, Meijer, Laurent, Golsteyn, Roy M.

Journal:

Year:

2013

Language:

english

File:

PDF, 672 KB

english, 2013

36

Cell Cycle Regulation of the Activity and Subcellular Localization of PLK1, a Human Protein Kinase Implicated in Mitotic Spindle Function

Roy M. Golsteyn, Kirsten E. Mundt, Andrew M. Fry and Erich A. Nigg

Journal:

The Journal of Cell Biology

Year:

1995

Language:

english

File:

PDF, 1.57 MB

english, 1995

37

On the Synthesis and Destruction of A- and B-Type Cyclins during Oogenesis and Meiotic Maturation in Xenopus laevis

Hideki Kobayashi, Jeremy Minshull, Chris Ford, Roy Golsteyn, Randy Poon and Tim Hunt

Journal:

The Journal of Cell Biology

Year:

1991

Language:

english

File:

PDF, 1.14 MB

english, 1991

38

Natural product extracts of the Canadian prairie plant, Thermopsis rhombifolia, have anti-cancer activity in phenotypic cell-based assays

Kernéis, Sophie, Swift, Lucy H., Lewis, Cody W., Bruyère, Céline, Oumata, Nassima, Colas, Pierre, Ruchaud, Sandrine, Bain, John, Golsteyn, Roy M.

Journal:

Natural Product Research

Year:

2015

Language:

english

File:

PDF, 428 KB

english, 2015

39

Genotoxic Anti-Cancer Agents and Their Relationship to DNA Damage, Mitosis, and Checkpoint Adaptation in Proliferating Cancer Cells

Swift, Lucy, Golsteyn, Roy

Journal:

International Journal of Molecular Sciences

Year:

2014

Language:

english

File:

PDF, 755 KB

english, 2014

40

Human cells enter mitosis with damaged DNA after treatment with pharmacological concentrations of genotoxic agents

Kubara, Philip M., Kernéis‑Golsteyn, Sophie, Studény, Aurélie, Lanser, Brittany B., Meijer, Laurent, Golsteyn, Roy M.

Journal:

Biochemical Journal

Year:

2012

Language:

english

File:

PDF, 1.09 MB

english, 2012

41

Radiosensitization by Chir-124, a selective Chk1 inhibitor: Effects of p53 and cell cycle checkpoints

Tao, Yungan, Leteur, Céline, Yang, Ceyao, Zhang, Ping, Castedo, Maria, Pierré, Alain, Golsteyn, Roy M., Bourhis, Jean, Kroemer, Guido, Deutsch, Eric

Journal:

Year:

2009

Language:

english

File:

PDF, 1.80 MB

english, 2009

42

Cytotoxic amounts of cisplatin induce either checkpoint adaptation or apoptosis in a concentration-dependent manner in cancer cells

Swift, Lucy H., Golsteyn, Roy M.

Journal:

Biology of the Cell

Year:

2016

Language:

english

File:

PDF, 1.49 MB

english, 2016

43

Cancer cells that survive checkpoint adaptation contain micronuclei that harbour damaged DNA

Lewis, Cody W., Golsteyn, Roy M.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.42 MB

english, 2016

44

Inhibition of Chk1 Kills Tetraploid Tumor Cells through a p53-Dependent Pathway

Vitale, Ilio, Galluzzi, Lorenzo, Vivet, Sonia, Nanty, Lisa, Dessen, Philippe, Senovilla, Laura, Olaussen, Ken A., Lazar, Vladimir, Prudhomme, Michelle, Golsteyn, Roy M., Castedo, Maria, Kroemer, Guido

Journal:

Year:

2007

Language:

english

File:

PDF, 1018 KB

english, 2007

45

G2/M-Phase Checkpoint Adaptation and Micronuclei Formation as Mechanisms That Contribute to Genomic Instability in Human Cells

Kalsbeek, Danî, Golsteyn, Roy

Journal:

International Journal of Molecular Sciences

Year:

2017

Language:

english

File:

PDF, 1.49 MB

english, 2017

46

Emerging Anti-Mitotic Activities and Other Bioactivities of Sesquiterpene Compounds upon Human Cells

Bosco, Alessandra, Golsteyn, Roy

Journal:

Year:

2017

Language:

english

File:

PDF, 3.86 MB

english, 2017

47

Meet Our Editorial Board Member:

M. Golsteyn, Roy

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 483 KB

english, 2016

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